Expert Bioinformatician

Are you an experienced Bioinformatician with strong project leadership skills and the ability to independently drive complex initiatives? Do you thrive in fast-paced, dynamic environments and adapt easily to shifting business priorities?

If this sounds like you and you are driven by purpose, join the SOPHiA GENETICS Tertiary Development Team as our Expert Bioinformatician, and enable us to make a positive impact on the outcomes for cancer and rare disease patients worldwide. 

This role is a hybrid opportunity, requiring 3 days onsite our corporate office in Rolle, CH.

Our Mission

We believe there is a smarter, more data-driven way to make decisions in healthcare and our cloud-native AI powered SOPHiA DDM Platform makes that vision a reality on a daily basis. You will have direct input to our mission to democratize data-driven medicine for the ultimate benefit of cancer and rare disease patients across the globe.

Your Mission

As our Expert Bioinformatician, you will lead the development, optimization, and scaling of tools and algorithms that enable the clinical interpretation of genomic data, playing a key role in delivering precision diagnostics at scale (note: this role does not involve machine learning development).

The vale you bring

• Design, develop, and maintain robust, scalable tools and algorithms for genomic annotation and variant interpretation. 

• Drive initiatives to enhance the efficiency, reproducibility, and scalability of our development processes. 

• Lead efforts to strengthen code testing frameworks and documentation standards, ensuring compliance with internal and external quality requirements. 

• Act as the primary liaison between the Tertiary Development team and other cross-functional teams (e.g., pipeline development, TECH, clinical affairs, software engineering) to coordinate deliverables. 

• Provide regular project updates and technical insights to the Director of Pipeline Development and the executive leadership team. 

Requirements

• PhD in Bioinformatics, Computational Biology, Human Genetics, or a related field, with relevant industry or postdoctoral experience. 

• Proficient in Python Cpp or R, SQL, Git, and Bash.  

• Proficiency in C++ or R is a plus.

• Extensive experience with NGS data analysis, high-performance computing (HPC) environments, bioinformatics workflows, parallelization, and containerization (e.g., Docker, Singularity). Experience with NGS data analysis is a plus.

• Demonstrated knowledge of variant calling, annotation, and interpretation of germline and somatic variants in human genomes. 

• Strong grasp of modern software development practices, including CI/CD, unit testing, code reviews, and reproducible research principles.
• Strong project leadership and cross-functional coordination skills, with a proven ability to drive complex projects independently. 

• Effective communication and collaboration skills in a multicultural and interdisciplinary environment. 

• Comfortable working in a fast-paced, dynamic setting, with the flexibility to adapt to shifting business priorities. 

Benefits

You will be joining an organization with the patient at the heart of every decision and action, driven by purpose as we pursue exponential growth.

Business recognition and accolades include: 

• World's most innovative companies (Top 10)
• World's smartest companies (Top 50) 
• 100 Best Places to Work in Boston (2022-2025)
• Top 10 European Tech Startup
• Top 10 European biotechs startup to watch
• Top 25 East-Coast Biotech to watch

Our benefits package is comprehensive, but varies internationally in-line with local standards and laws. You can discuss a full breakdown with us, but as a brief overview:

• Sickness and Accident coverage through Helsana
• Meal Vouchers at 90CHF PM with our partner cafeteria
• A fun and engaging work environment, with Rest & Entertainment space, full stocked free coffee machine and free fruit
• Free parking in an easy to access location
• A strong social committee whose purpose is to make SOPHiA GENETICs both enjoyable as well as rewarding
• As our global HQ, you’ll have direct interaction and exposure to senior leadership and our executive team locally

Our DNA

Like the strands of DNA itself, SOPHiA GENETICS and the team are deeply interconnected and reliant on each other to deliver. There are common threads across the team. Things that bind us together. Those things are Relentless Curious; Resilient & Nimble and Fearlessly Adventurous 

Our Virtues

At SOPHiA GENETICS we established our 7 Virtues to clarify how our principles show up each day through action.  We Decide; We Do; We Collaborate; We Innovate; We Empower; We Adapt and We Learn.

At the centre of our Virtues is our Mantra, We Care, which provides a constant reminder of the compassionate, benevolent, and hopeful nature of our mission and how it should be threaded through each of our Virtues and everything we do. Learn more about our DNA and Virtues on our Careers portal

Starting Date: ASAP 

Location: Rolle, Switzerland - (Hybrid, 3 Days Per Week)

Contract: Permanent